According to a study that is published in PLoS Medicine’s Special Issue on Dementia shows that low levels of polyunsaturated fatty acids in the brain may speed up the development of Alzheimer’s disease. It is therefore vital not to shy away from dietary fats. What is important, however, is to consume unspoiled sources of omega-3 and omega-6 fatty acids in the proper balance. Polyunsaturated fatty acids have numerous functions in the brain, on which our nervous system, cardiovascular system, memory, learning ability, and lingual skills depend.

Alzheimer’s disease causes brain malfunctions, and the condition is the leading cause of dementia. According to a studies of humans and mice, there may be a link between borderline vitamin A deficiency and an increased risk of Alzheimer’s disease. Vitamin A is important for the immune system, but it is also a powerful antioxidant that protects neurons and other cells. Vitamin A deficiencies are widespread globally. In the industrialized countries, we mainly see vitamin A deficiencies in connection with unbalanced diets, ageing, and chronic illness.

Studies show that large quantities of B vitamins are able to slow mild cognitive impairment, which is an early stage of dementia and Alzheimer's disease. A more recent study suggests, however, that B vitamins are not effective, unless the body is properly supplied with the omega-3 fatty acids that are found in fish oil.

Apparently so. According to a new study published in the journal Alzheimer’s and Dementia, older people who take a daily multivitamin supplement for several years are far less likely to develop dementia, Alzheimer’s disease, and other types of cognitive decline. The new study supports earlier research where it has been seen that the different vitamins and minerals increase cerebral blood flow and protect neurons. It pays off to choose high-quality supplements to make sure that the nutrients are properly absorbed in the body.

The number of seniors in the world is growing steadily which means a surge in problems like cardiovascular disease, cancer, respiratory illnesses, overweight, diabetes, rheumatism, dementia, and Alzheimer’s disease. These diseases that have a widespread impact on human lives and are a burden to society are often linked to chronic inflammation. A group of scientists therefore decided to look closer at studies that have found a positive effect of the omega-3 fatty acids EPA and DHA on cognitive functioning, maintenance of muscle mass, and prevention and treatment of a host of serious diseases that are related to ageing. It is vital to start supplementing early and to take the right doses, according to the new review article published in Nutrients.

Vitamin B3 plays a crucial role in our brain and nervous system, and it is also important for our mental well-being. Studies suggest that lack of vitamin B3 increases the risk of dementia, Alzheimer’s disease, Parkinson’s disease, and schizophrenia. Moreover, epidemiological studies show that diets without vitamin B3 in them tend to cause aggression and an increased rate of homicide. Too little B3 can be caused by dietary shortages and environmental factors, but it also appears that some people have an increased need for the nutrient due to genetic variations and problems with utilizing the vitamin.

Brain cells (neurons) contain comparatively large concentrations of vitamin C, a nutrient that helps us maintain a healthy nervous system in a number of different ways. Scientists have discovered that lack of vitamin C can affect the brain’s neural signaling. Consequently, a vitamin C deficiency can impair memory and other cognitive skills in seniors. This was demonstrated in a study from Flinders University in Australia. Mild cognitive impairment is widespread among older people and represents an early stage of dementia so it is important to get plenty of vitamin C every day throughout life.

it’s the ultimate and essential “brainwash”

Groundbreaking research reveals that the human brain is detoxified during our sleep. On the other hand, toxins accumulate in the brain if we suffer from sleep disturbances, increasing our risk of dementia, Alzheimer’s disease, stroke, and numerous other conditions. If you are not helped by the most common guidelines for better sleep, supplementing with the “sleep hormone” melatonin may be an obvious solution that even offers plenty of positive “side effects.”

- which may lead to serious physical and mental diseases

Recent studies reveal that around 20% of people who take metformin, a drug against type 2 diabetes, are vitamin B12 deficient (or borderline deficient). Lack of vitamin B12 may cause anemia, increased risk of osteoporosis, and symptoms of the nervous system that may be confused with ageing processes. It even looks as if lifestyle changes may have a more positive effect on blood sugar management.

The number of older people is on the rise, and so is the number of people who suffer from dementia and die as a result of this condition. If you increase your dietary intake of magnesium, however, and get more than what is officially recommended, it helps keep your brain sharp and prevents dementia, according to a large population study that is published in European Journal of Nutrition. Many older people don’t eat enough and even take different kinds of medicine that block the body’s uptake and utilization of magnesium. So, how does magnesium affect the brain and nervous system? And how much do we need to stay mentally alert throughout life? Those are the questions.

Dr. Yamagishi and colleagues from Japan's University of Tsukuba in a new study has used data from 6,000 middle-aged Japanese, and for the first time have been able to show that low levels of coenzyme Q10 in the blood are strongly associated to an increased risk of disabling dementia.

Neurological disorders such as Alzheimer’s disease, dementia, depression, Parkinson’s disease, stroke, migraine, and fibromyalgia are rather common. These conditions are a result of imbalances in the nervous system, and they are often insidious. In a new review article that is published in Frontiers in Neuroscience, researchers have studied Q10’s role in the different neurological disorders. The reason for this is that Q10 is important for cellular energy turnover and serves as an antioxidant that protects the circulatory system and the nerve cells against oxidative damage. As we grow older, our endogenous Q10 synthesis decreases, and certain diseases and medical drugs also impair the body’s Q10 synthesis.

The number of seniors worldwide is increasing and more and more are affected by Alzheimer’s disease, the leading cause of dementia. We should therefore focus much more on this health problem that comes with an enormous human and socio-economic price tag. According to a new meta-analysis, supplementation with B vitamins appears to prevent or delay mild cognitive impairment in older people, which is normally an early sign of Alzheimer’s disease. In fact, supplementation with B vitamins may even represent an inexpensive therapy form with a huge potential.

- and widespread deficiency has serious consequences

It is commonly known that vitamin C has an essential role in our connective tissue and immune defense. However, vitamin C is also vital for the brain. This was demonstrated in a new Australian study of the link between vitamin C and cognitive functions like memory, lingual skills, calculation, and orientation. The scientists also point to the fact that vitamin C deficiency is rather common in western countries, either due to dietary factors or because of conditions that increase the need for the nutrient.

Alzheimer’s is a growing health burden worldwide, and diet appears to play a major role. A large meta-analysis published in Frontiers in Aging Neuroscience recently revealed that patients with Alzheimer’s disease have lower levels of magnesium in their blood and cerebrospinal fluid compared to healthy controls. This suggests that being magnesium-deficient may be a risk factor in Alzheimer’s disease.

Undernourishment typically affects the elderly, those with diseases, addicts, and people with eating disorders. The condition increases the risk of serious diseases and repeated hospitalizations and is an enormous economic burden to society. Many undernourished people suffer from loss of appetite, a problem that can often be stimulated with improved diets and supplements of B vitamins.

Alcohol is one of the most compromising factors when it comes to public health, and alcohol abuse comes at an enormous cost, both to the individual and to society. A large alcohol consumption contributes as a factor to insidious dementia, but according to a new study from Taiwan, supplementing with vitamin B1 (thiamine) may prevent alcohol-induced dementia. The scientists that have conducted the study therefore point to vitamin B1 supplementation as having an important role in the treatment plan for people with alcohol abuse problems and to prevent dementia from developing or progressing.

Dementia is on the rise across the globe but according to a study from University of South Australia, vitamin D may have the potential to pull the brake on the degenerative processes. The scientists have observed a direct link between the widespread problems with vitamin D deficiency and the increasing rate of dementia. At the same time, they assume that optimizing people’s vitamin D status in the blood may help prevent millions of dementia cases worldwide. The need for vitamin D varies from person to person, it should be noted, and many people have a higher need for the vitamin than what is officially recommended.

Vitamin D plays a major role in our health. The main focus, however, is on vitamin D’s importance for bones, while many health professionals are totally unaware of the nutrient’s other essential functions. According to a review article published in Nutrients, half the global population has low vitamin D levels in the blood, which increases the risk of cardiovascular disease, hypertension, cancer, type 2 diabetes, Alzheimer’s disease, respiratory infections like COVID-19, and early death. The authors also mention that vitamin D science is often inadequate or misleading because studies focus on supplementation rather than looking at blood levels of 25(OH)D. Consequently, trials are often made with far too small vitamin D doses or with too a short a trial period. In either case, blood levels of vitamin D fail to reach their optimum. What is more, levels of 25(OH)D in the blood should ideally be above 75 nmol/L in order to protect against cardiovascular disease, cancer, and early death. Because this threshold level is higher than the official threshold levels, the scientists recommend high-dosed vitamin D levels as a way to reach an optimal nutrient status.

- and other types of organ damage

Vitamin K occurs naturally in different forms. The vitamin is primarily known for its role in blood coagulation, but a team of German scientists has found a new type of vitamin K. This form serves as a very particular type of antioxidant that counteracts cell death caused by a process called ferroptosis. Because ferroptosis is involved in the development of Alzheimer’s disease, acute organ damage, and other diseases, the researchers see a whole new potential for vitamin K in the prevention and mitigation of ferroptosis-related ailments. Earlier studies even suggest that selenium-containing antioxidants also protect against cell death caused by ferroptosis.

The risk of dementia and neurological disorders increases with age. Diet plays an important role and it is assumed that the widespread lack of vitamin K2is particularly relevant. In order to test this hypothesis, a group of scientists measured levels of vitamin K2 in the brains of deceased seniors. They found significantly fewer cases of cognitive decline, dementia, and Alzheimer’s disease in brains with higher K2 levels. This has something to do with the fact that vitamin K2 counteracts atherosclerosis, accumulation of harmful protein, and brain inflammation. The study is published in the journal Alzheimer’s & Dementia and sheds a whole new light on vitamin K’s potential role in brain health and the importance of getting enough of this nutrient.