Q10 is important for cellular energy turnover, and it is also a powerful antioxidant that protects cells and the circulatory system. We synthesize most of our own coenzyme Q10. According to a new in vitro study that is published in Scientific Reports, commonly used medical drugs such as the bisphosphonates, alendronate and zoledronate, for treating osteoporosis block the body’s Q10 synthesis, thereby impairing the energy production in cells, the antioxidant defense, and other metabolic processes. Earlier research has shown that cholesterol-lowering statins lower the endogenous Q10 synthesis, causing side effects such as tiredness, aching muscles, and impotence. It may therefore be a good idea for patients on this type of medication to take a Q10 supplement to prevent or mitigate the adverse effects.

Inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis are becoming more and more common, even among young people. Diet, gut flora, and immune defense play a major role. Also, patients with inflammatory bowel disease seem to have lower blood levels of vitamin D, which is linked to the chronic inflammatory state and the progression of the disease. This was demonstrated in a study that was published recently in the science journal Medicine.

Everybody is exposed to heavy metals and other environmental toxins. They are present in the water, the air, our diet, in cosmetics, tobacco smoke, medicine, and countless other sources. These toxins increase our risk of cancer, neurological disorders, thyroid disease, autoimmune disease, and numerous other health problems. Also, the combination of different toxins causes a “cocktail effect” that we know very little about. According to a Spanish study of mice, which is published in Science of The Total Environment, a selenium-enriched diet has a protective effect.

Non-alcoholic fatty liver disease (NAFLD) that is linked to overweight and type 2 diabetes may eventually cause critical liver inflammation, liver fibrosis, and liver cancer. The diet plays a major role, and scientists from Oregon State University have observed that the omega-3 fatty acids that we get from oily fish are able to fight this harmful liver condition. This has enormous therapeutic value because there are currently no available therapies. It is also important to avoid altogether or limit your intake of refined carbohydrates and refined omega-6 fatty acids from plant oil.

Having too little selenoprotein P in your blood increases the risk of heart failure, according to a Swedish population study, in which the authors look closer at selenoprotein P’s role as a marker of the body’s selenium status and as a precursor of other selenoproteins. We need more than 100 micrograms of selenium daily to properly saturate selenoprotein P, but because the European soil is low in selenium it is difficult to get enough from the diet.

According to WHO, the number of overweight children has reached epidemic proportions. Overweight children risk being overweight as adults and develop hypertension, cardiovascular disease, type 2 diabetes, chronic inflammation, and other metabolic disturbances. Apparently, overweight individuals often lack vitamin D, a nutrient that is important for regulating weight, inflammation, and many metabolic processes. This was pointed out in an Italian study published in Nutrients, where the authors address vitamin D’s role in health and explain why so many overweight people are vitamin D-deficient.

- and oxidative stress

The body uses inflammation as part of its normal immune response to infections and tissue damage. If inflammation becomes chronic, however, it can be extremely dangerous. What happens is that it bombards the body with free radicals. This leads to oxidative stress and increases the risk of cell damage, overweight, and chronic diseases like type 2 diabetes, cardiovascular disease, autoimmune diseases, and different cancer forms. Diet and lifestyle play a major role, and according to a meta-analysis published in Frontiers in Pharmacology, Q10 supplementation can lower several markers of inflammation and oxidative stress.