According to Bruce Ames, an American biochemist, ageing processes are largely due to lack of nutrients. One important contributing factor is the fact that our uptake and utilization of vitamins and minerals decrease with age. In addition, a lot of different types of medicine block our ability to utilize different nutrients. As a result of this, many of our enzyme processes slow down, making our cells increasingly vulnerable and that increases our risk of disease. Nonetheless, there is a lot we can do to optimize our intake and utilization of nutrients, particularly with respect to vitamin B12, vitamin D, calcium, iron, selenium, and zinc. It is also worth taking a look at Q10 for energy turnover and melatonin for healthy sleep. Our endogenous synthesis of both compounds decreases with age.

Antioxidants such as vitamins C and E are known to be inversely related to type 1 diabetes, which is an autoimmune disease. In a new Swedish study that is published in Nutrients, scientists have found that vitamin E also protects against type 1,5 diabetes, which is similar to type 1 and type 2 diabetes because it involves both autoimmune reactions and insulin resistance. The scientists list different foods that are rich in vitamin E and also describe how vitamin E protects the pancreas against autoimmune attacks and oxidative stress.

It is estimated that one billion people worldwide lack selenium. This has fatal consequences for public health because it increases the risk of virus infections, thyroid disorders, cardiovascular diseases, cancer, neurological disorders, and involuntary infertility. Adding to that problem is the fact that mercury, a known environmental toxin, throws a wrench into selenium’s different functions. In the following, we have compiled a long list of studies that look closer at the consequences of selenium deficiency and the advantage of optimizing the body’s selenium status with help from supplements.

Having higher blood levels of selenium, an essential trace element, increases a breast cancer patient’s chances of 10-year survival, according to a Polish population study that is published in the science journal Nutrients. Also, earlier research has shown that supplementation with selenium yeast can lower the risk of contracting a variety of different cancer forms. The agricultural soil in Europe is very low in selenium and that is one of the reasons why selenium deficiencies are so common. The question is how much selenium we need to optimize levels in the blood.

COVID-19 represents a serious global threat against public health and the economy because we still lack a vaccine and effective therapies. When COVID-19 becomes life-threatening it is primarily because the immune defense overreacts with a cytokine storm and hyperinflammation that destroys healthy tissue in the lungs, the circulatory system, and other places. Older people and heart failure patients already suffer from chronic low-grade, uncontrolled inflammation, to which nutrient deficiencies contribute and make the patients increasingly vulnerable. This also applies to people with metabolic syndrome and diabetes, many of which are overweight. For that reason, scientists affiliated with universities and research centers in Norway, Sweden, and Russia have searched the scientific literature to find studies that focus on whether supplementation with vitamin D, selenium, and zinc can help prevent a COVID-19 infection from escalating and becoming life-threatening.

Everyone is affected by electromagnetic radiation from cell phones, device screens, the electricity supply and other electric systems. The brain’s neurons are particularly vulnerable, especially because electromagnetic radiation can increase the neuronal uptake of calcium ions, which makes the neurons overactive and may even cause them to perish. A study published in News Medical Life Sciences shows that too much calcium in the brain increases the risk of Alzheimer’s disease and digital dementia in young individuals. The increased electromagnetic radiation also generates loads of free radicals in the body that can cause oxidative stress and cellular damage because it outperforms the body’s different antioxidants. This was described in an article published in The Journal of Microscopy & Ultrastructure that also mentions how electromagnetic radiation can cause stress, headaches, fatigue, anxiety, and other symptoms.

The majority of sexually active people contract HPV (human papilloma virus), of which there are several types. Normally, the infection goes away by itself but in some cases it becomes chronic. This increases the risk of serious cell changes in the cervix which, in worst case, can result in cervical cancer. An American study has found that having adequate levels of five different antioxidants – albumin plus vitamins A, B2, E, and folic acid – may lower papilloma virus infections that are linked to cervical cancer.

Selenium deficiency is widespread in Europe and many other parts of the world, negatively impacting public health. On the other hand, adequate selenium intake through diet and supplements can reduce the risk of cardiovascular diseases, diabetes, metabolic disorders, cancer, and early death. A study published in Frontiers in Nutrition suggests that older individuals have an increased need for selenium.

Critically ill patients often suffer from inflammation and oxidative stress, which is an imbalance between harmful free radicals and protective antioxidants. In worst case, this may result in tissue damage and organ failure. It turns out vitamin C is a powerful antioxidant with a therapeutic potential. According to a new systematic review article and meta-analysis, therapy with large quantities of intravenous vitamin C helps shorten the duration of the hospital stay for critically ill patients without any side effects.

Kidney stones is a painful and quite common problem. The diet plays a major role and according to a large American population study published in Nutrients, selenium may help prevent the condition. The authors mention that selenium-containing proteins and antioxidants have preventative mechanisms and due to the widespread problems with selenium-depleted farmland, they say that selenium supplementation may be a good way to prevent and manage kidney stones and other pathological changes.

Millions of people take painkillers such as Panadol or Calpol that contain paracetamol, and an estimated one billion people or so lack selenium due to nutrient-depleted farmland. This is an unfortunate cocktail because being deficient of selenium increases the risk of using paracetamol, so even the recommended dosage burdens the liver to such an extent that it causes toxicity and increase the risk of side effects. This was demonstrated in a collaborative study carried out by Bath University in England and Southwest University in China.

It is commonly known that pregnant diabetics have an increased risk of developing an eye disease called diabetic retinopathy. The diet plays a major role and it appears that a vitamin C deficiency increases the risk, according to a Danish study of pregnant type 1 diabetics that is published in the journal Antioxidants. The authors also mention that vitamin C is a vital antioxidant that protects cells and tissues against oxidative stress caused by free radicals.

- and supplements may have therapeutic value

Hereditary hemochromatosis is a group of diseases that involve iron accumulation in the body. This leads to oxidative stress and tissue destruction which may affect the liver and other organs. According to a new Argentinian study, patients with hereditary hemochromatosis lack Q10 in their blood. Because Q10 is of vital importance to the cellular energy turnover and it also serves as a powerful antioxidant against oxidative stress, a Q10 deficiency will contribute to the disease. This, the researchers behind the new study explain, is why Q10 may represent a new and safe agent for treating the condition.

According to WHO, sepsis is the third-most common cause of death, following cardiovascular disease and death. Sepsis is a result of the immune defense overreacting to an infection in the bloodstream. According to a new Slovakian study published in Bratislava Medical Journal, if you start supplementing with Q10 early in the treatment phase, it may reduce the symptoms and improve the chances of survival. Read more about another nutrient that contributes to the prevention of sepsis.

- and oxidative stress

The body uses inflammation as part of its normal immune response to infections and tissue damage. If inflammation becomes chronic, however, it can be extremely dangerous. What happens is that it bombards the body with free radicals. This leads to oxidative stress and increases the risk of cell damage, overweight, and chronic diseases like type 2 diabetes, cardiovascular disease, autoimmune diseases, and different cancer forms. Diet and lifestyle play a major role, and according to a meta-analysis published in Frontiers in Pharmacology, Q10 supplementation can lower several markers of inflammation and oxidative stress.

Cataracts is one of the leading causes of vision impairment and blindness. The risk is increased by old age and diabetes. According to a new study that is published in Frontiers in Nutrition, a relatively high selenium intake can protect against the disease. The scientists mention that because of selenium’s unique antioxidant properties this nutrient protects the cells in the eye and in other places against free radical damage and oxidative stress.

Everybody is exposed to heavy metals and other environmental toxins. They are present in the water, the air, our diet, in cosmetics, tobacco smoke, medicine, and countless other sources. These toxins increase our risk of cancer, neurological disorders, thyroid disease, autoimmune disease, and numerous other health problems. Also, the combination of different toxins causes a “cocktail effect” that we know very little about. According to a Spanish study of mice, which is published in Science of The Total Environment, a selenium-enriched diet has a protective effect.

Selenium supports a number of different selenium-dependent proteins that are important for our energy turnover, metabolism, immune defense, fertility, and antioxidant protection. Selenium also has a special affinity for mercury and is therefore able to bind to this heavy metal and counteract its harmful impact on the brain, the nervous system, and other tissues. Once selenium is bound to mercury, however, the different selenoproteins are no longer able to use it. We are all exposed to a certain amount of mercury and that may result in a borderline deficiency of selenium. The problem is that other factors weigh in such as selenium-depleted crops because of the lack of selenium in the European farmland. What is important to realize is that mercury toxicity is insidious and certain fish such as predatory fish and whales in the upper part of the food chain contain large concentrations of mercury. However, therapeutic doses of selenium can prevent the toxic effect of the heavy metal, according to a new review article published in Scientific Research.

Over the past decades, numerous studies have linked low selenium levels in the blood to cardiovascular disease, cancer, increased risk of infection, thyroid disorders, and several other diseases. Due to the widespread problems with selenium deficiency, supplementation with this nutrient is of potential value to our general health. In a review article that is published in Oxidative Medicine and Cellular Longevity, the authors look at selenium’s role in connection with a host of different diseases and metabolic disorders.

Regular sport is good for you, whereas arduous training and high-performance sport can result in physical injuries, infections, chronic inflammation, and serious diseases due to oxidative stress. This phenomenon occurs as a result of the increased energy turnover, which produces an excess of free radicals that cause damage to cells and tissues. Oxidative stress is also associated with impaired performance, poor restitution, and faster ageing. Our only natural defense against free radicals is the presence of antioxidants, and it is especially things like vitamin C, vitamin E, selenium, zinc, Q10, omega-3 fatty acids, and turmeric that protect against oxidative damage and improve recovery time. According to a review article published in Nutrients, supplements with the right doses of different nutrients can also help boost your physical and mental performance.

Selenium is involved in enzymes that activate thyroid hormones. It is also part of several antioxidants that protect cells and the circulatory system from damage caused by free radicals. Additionally, selenium is crucial for the optimal utilization of Q10, which plays a role in cellular energy metabolism. However, selenium intake in many European countries is too low, mainly due to depleted soil. At the same time, the body’s endogenous production of Q10 declines significantly with age. This can lead to metabolic disorders, atherosclerosis, fatigue, and other deficiency-related conditions. According to a follow-up study published in BMC Medicine, supplementation with selenium and Q10 has a positive effect on thyroid hormones, circulation, quality of life, and lifespan.

The kidneys cleanse our blood. Well-functioning kidneys are vital for the circulatory system and good health in general. Normal functioning of cells, including kidney cells, hinges on a host of different selenium-containing proteins and coenzyme Q10. Studies show that older people in many parts of the world, Europe included, have deficiencies of both substances. Therefore, a team of Swedish scientists conducted a study where they looked at selenium status and kidney function in a group of seniors. They gave selenium yeast and coenzyme Q10 or placebo to the participants for a period of four years. The results showed that the supplemented group as compared with the placebo group had improved kidney function according to several parameters. The positive effect on cellular energy metabolism, inflammation, and oxidative stress was attributed to the two supplements. The study is published in the science journal Nutrients.

Both physical traumas and critical illnesses are associated with inflammation and oxidative stress where free radicals can cause potentially life-threatening damage to cells and tissues. Traumas are estimated to be the cause of one in ten deaths. New research suggests that early intervention with selenium may shorten the hospital stay including the days spent in intensive care and reduce total mortality. This was shown in a study published in Frontiers in Nutrition where the researchers looked closer at selenium’s unique antioxidant properties and anti-inflammatory effect.

A type of cancer called chronic myeloid leukemia is characterized by an overproduction of white blood cells that can lead to symptoms like fatigue, infections, and other complications. Another characteristic feature of chronic myeloid leukemia is chronic inflammation that contributes to the disease progression. Vitamin C, however, appears to counteract the inflammation, according to a Brazilian in-vitro study that is published in Nutrients.

Air pollution is a serious health threat that affects the entire world. Previous studies show that it increases the risk of cardiovascular disease, among other things. We need new strategies for protection, and a recent Chinese study conveniently reveals that supplementation with vitamin Ccan protect the cardiovascular system against oxidative stress and other harmful impacts from air pollution. What we need to find out is how much vitamin C it takes to obtain a therapeutic effect.

The trace element selenium has a vital yet overlooked role in ensuring a well-functioning immune system, and the widespread problems with selenium deficiency increase the risk of dying of COVID-19, according to a large German study that is published in the science journal Nutrients. The scientists therefore conclude that determining the patients’ blood selenium levels may provide vital diagnostic information. Also, the researchers conclude that it may be necessary to include selenium supplements in the treatment of COVID-19, especially with older people, diabetics, and those with chronic diseases that are at particular risk of life-threatening complications. The agricultural soil in Europe and other parts of the world contains relatively little selenium, which is why it is imperative to focus more on getting adequate amounts of this essential nutrient for the sake of preventing COVID-19 and other viral infections. It appears that the official recommendations – the so-called reference intake levels or RI – are not sufficient to meet the body’s actual requirements.