Selenium is a trace element that supports well over 25 different selenoproteins, which are important for our energy turnover, blood sugar balance, metabolism, cell protection, and a host of other essential functions. A group of scientists from Rutgers University in New Jersey, USA, has just uncovered the mechanisms involved in getting selenium into the “engine room” of the cells, from where it is metabolized into the different selenoproteins. According to the scientists, this new insight into the metabolism of selenium may lead to new therapies that can treat a variety of diseases such as diabetes, metabolic disorders, and cancer.

Blood levels of vitamin D serve as an early indicator of future health problems such as cardiovascular disease, osteoporosis, and cancer, according to a review article that was presented recently to the European Society of Endocrinology. Lack of vitamin D is rather common and a threat to public health, which is why the scientists suggest measuring levels of total vitamin D and free vitamin D in the blood. By optimizing levels of the nutrient in the blood it is possible to prevent a host of different lifestyle diseases as well as early death. It is not enough just to take any random vitamin D supplement. It must contain the right dose and have good absorption in order to be able to optimize vitamin D levels in the blood.

Calcium and vitamin D normally get all the attention when it comes to bone health. However, magnesium also plays a crucial, but often overlooked, role. This was demonstrated in a large population study that is published in Frontiers in Nutrition. The study links lower dietary magnesium to a greater risk of developing osteoporosis, especially for women aged 55 years and older. Osteoporosis normally takes many years to develop so it is vital to get plenty of magnesium from the diet or from supplements. Also, beware that excessive calcium intake, antacids, and diuretics block the body’s ability to absorb and utilize magnesium.

Immunotherapy has a special potential when used to treat cancer, which is because this particular type of therapy inhibits special molecules that block the body’s own defense mechanism against cancer cells. A team of scientists from Texas has discovered that vitamin E inhibits a particular molecule, thereby boosting the immunotherapy’s ability to stimulate important white blood cells. The scientists made this discovery by analyzing clinical data and in-depth laboratory studies. Vitamin E may play a future role in the prevention and treatment of cancer.

Many critically ill patients lack vitamin D to an extent that can be life-threatening. This also goes for patients hospitalized with COVID-19. A large meta-analysis concludes that supplementation with vitamin D can lower all-cause mortality and reduce the duration of patients’ stay in intensive care. In the meta-analysis, the researchers look at the mechanisms that enable vitamin D to regulate inflammation and oxidative stress, which can lead to organ failure in critically ill patients.

Primary Q10 deficiency is a rare dysfunction where the body’s missing ability to synthesize Q10 can lead to a rare type of nephrotic disease that cannot be treated with medicine. According to a new study that is published in Kidney International, however, it appears that Q10 supplementation can reduce the kidneys’ protein excretion, protect renal function, and lower mortality. Based on their findings, the scientists conclude that all patients with primary Q10 deficiency should ideally receive early and life-long Q10 therapy in order to prevent the disease from progressing and to avoid future organ damage.

Non-alcoholic fatty liver disease (NAFLD) is an insidious disease that is spreading like a bushfire, and it is typically seen in connection with overweight. Many people with the disease develop a type of liver inflammation and scarring that can be potentially life-threatening. According to a study that is published in Journal of Hepatology, supplementation with vitamin B12 and folic acid (vitamin B9) can counteract the development of inflammation and scarring by lowering levels of the amino acid homocysteine. The scientists behind the study looked closer at homocysteine’s role in the pathogenicity of the disease.

Cardiovascular disease is the leading cause of death worldwide but a new Dutch study has revealed that older patients who have suffered a previous heart attack can lower their risk of early death caused by cardiovascular disease and other causes by getting enough magnesium. Magnesium deficiencies are rather common because of unhealthy eating habits, and there are also certain types of medicine that impair the body’s ability to absorb and utilize magnesium.

Babies and small children are less likely to develop croup if their mothers have taken high-dosed vitamin D and fish oil during their pregnancy, according to a Danish study, where scientists have studied this relation for the very first time. Vitamin D and fish oil also benefit the child’s immune defense and counteract the inflammation in the respiratory system that triggers croup. The two supplements even have a positive impact on the child’s bone health and nervous system, and they also help prevent asthma.

Cystic fibrosis is a serious condition that affects the respiratory tract. It comes with chronic inflammation and sticky mucous and is known to cause early death. Patients who take high-dosed vitamin C supplements seem to make better use of vitamin E, which is also an antioxidant, and the result is less inflammation. This was seen in a study from Oregon State University. The scientists mention that taking extra vitamin C is also relevant for smokers and patients with metabolic disease.

Because COVID-19 mutates from time to time, a vaccine can only provide temporary protection. Also, studies suggest that what makes COVID-19 dangerous is when the immune defense overreacts by launching so-called hyperinflammation that can damage the circulatory system and healthy tissues. The omega-3 fatty acids in fish oil turn out to have the potential to prevent COVID-19 infections from becoming life-threatening due to hyperinflammation. That way, fish oil can also help improve survival, according to a review article that is published in International Journal of General Medicine.

Vitamin B3 plays a crucial role in our brain and nervous system, and it is also important for our mental well-being. Studies suggest that lack of vitamin B3 increases the risk of dementia, Alzheimer’s disease, Parkinson’s disease, and schizophrenia. Moreover, epidemiological studies show that diets without vitamin B3 in them tend to cause aggression and an increased rate of homicide. Too little B3 can be caused by dietary shortages and environmental factors, but it also appears that some people have an increased need for the nutrient due to genetic variations and problems with utilizing the vitamin.