There are various forms of biotin and they all belong to the family of B vitamins. Biotin is synthesised from bacteria (including gut bacteria) and mold and yeast fungus, algae, and certain plants. Biotin is water-soluble and because it does not get stored in the body we depend on regular intake/production of the nutrient. Biotin is removed when boiled in water.

When cells convert the calories from food into energy, a variety of B vitamins, vitamin C, iron, magnesium, zinc, and Q10 are needed. This also means that a deficiency in one or more of these substances can result in mental and physical fatigue to a greater or lesser extent. The impaired energy metabolism of the cells also increases the risk of mood swings, concentration difficulty, infections, and other diseases. Modern lifestyle, ageing processes, medications, and other factors cause serious deficiencies, but these deficiencies can be corrected with help from dietary changes and relevant supplements.

According to a new study that is published in the British Journal of Nutrition, even minor zinc deficiencies may cause poor digestion, skin problems, and fatigue - and lead to numerous other health problems in the long run. You should therefore avoid zinc shortages, and people with poor diets, vegans, vegetarians, and older people should make sure to get enough zinc.

“After about one week of taking the Q10 capsules I could feel a huge difference. I sleep much less and have energy to enjoy life again,” says 23-year old Alan Piccini, who has been suffering from extreme fatigue and muscle aches ever since he was a child.

Perhaps so. More and more studies reveal that it helps to take large quantities of Q10 and a vitamin B3 derivate. Q10 and vitamin B3 are both essential for the body’s energy turnover, which takes place inside the mitochondria of the cells. A more recent study shows that taking supplements of the mentioned nutrients can also have a positive effect on the heart, which is the body’s central motor.

A team of scientists from Århus University Hospital has discovered that high-doses supplementation with vitamin B1 can help against chronic fatigue that is seen with chronic inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. High doses of vitamin B1 may even help against chronic fatigue in fibromyalgia and other neurological disorders. The scientists have not yet mapped out how the large vitamin doses affect the brain and energy levels and several theories are on the table.

The cellular energy turnover takes place inside some small powerhouses called mitochondria. The condition of these tiny structures is determining for our energy levels and health. That is why it is vital that the mitochondria are adequately supplied with all the necessary nutrients. Q10 and magnesium play a particularly important role.

Q10 is a key element in the cellular energy turnover and also serves as a protective antioxidant. The human body is able to make most of its own Q10 but as we grow older, our endogenous Q10 synthesis decreases, and this is also the case with certain diseases and as a result of using specific types of medicine. A large meta-analysis has shown that Q10 supplementation is able to reduce chronic fatigue in healthy individuals as well as in people with diseases. Apparently, taking larger doses for longer periods of time works best for energy levels. It is important to choose a Q10 supplement that has the right quality and comes with documentation to ensure that the Q10 molecules are absorbed properly in the blood and reach the energy-producing powerhouses of the cells.

Q10 is a unique and wonderful coenzyme with a key function in energy turnover and a role as a powerful antioxidant. The body produces the lion’s share Q10 for its own needs but the endogenous synthesis of the compound decreases with age. Moreover, cholesterol-lowering statins and bisphosphonates used to treat osteoporosis disrupt the body’s Q10 synthesis. Over the past decades, numerous studies have shown that Q10 supplementation can slow down the ageing process. Q10 is also useful in connection with heart failure and several other chronic ailments that typically occur in old age. This is described in a review article that is published in Mechanisms of Ageing and Development. With Q10 supplements, it’s important to choose pharmaceutical-grade products with documented quality and bioavailability.

Q10 is a unique compound with a key role in cellular energy turnover. It also serves as a powerful antioxidant. The body is able to synthesize most of the Q10 that it needs but as we grow older, our endogenous synthesis decreases, making us vulnerable in different ways. Cholesterol-lowering medicine and certain types of disease are also associated with lower levels of Q10 in the body. In a new review article, a group of scientists have scrutinized hundreds of Q10 studies that have been published in the years 2010-2020. They are able to conclude that Q10 is of particular importance to the heart, circulatory system, fertility, muscles, eyes and vision, and the ageing process. Things like migraines, chronic fatigue syndrome, and neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease are also addressed. The body has difficulty with absorbing Q10 from food and supplements so it is recommendable to always choose a pharmaceutical-grade Q10 preparation with documented bioavailability.

Hormonal imbalances have broad implications and increase the risk of chronic fatigue, overweight, impaired fertility, dry mucosa, hot flushes, slow metabolism, breast cancer, and many other problems. Lack of essential nutrients contributes to such disruptions of the sensitive hormone system. This is also the case with hormone-disrupting compounds.

Vitamin B3 is water-soluble and because it does not get stored in the body we depend on regular intake of the nutrient. Niacin is a common term for nicotinic acid and nicotinamide. The body's metabolism is able to synthesise part of its required niacin from vitamin B6 and tryptophan, an amino acid which is primarily found in meat. Vitamin B3 is destroyed by heating.

Vitamin B6, also known as pyridoxine, is converted to the active forms, pyridoxal phosphate and pyridoxamine phosphate. Vitamin B6 is water-soluble and because it does not get stored in the body we depend on regular intake of the nutrient. Vitamin B6 is destroyed by heating and light.