Many critically ill patients lack vitamin D to an extent that can be life-threatening. This also goes for patients hospitalized with COVID-19. A large meta-analysis concludes that supplementation with vitamin D can lower all-cause mortality and reduce the duration of patients’ stay in intensive care. In the meta-analysis, the researchers look at the mechanisms that enable vitamin D to regulate inflammation and oxidative stress, which can lead to organ failure in critically ill patients.

Primary Q10 deficiency is a rare dysfunction where the body’s missing ability to synthesize Q10 can lead to a rare type of nephrotic disease that cannot be treated with medicine. According to a new study that is published in Kidney International, however, it appears that Q10 supplementation can reduce the kidneys’ protein excretion, protect renal function, and lower mortality. Based on their findings, the scientists conclude that all patients with primary Q10 deficiency should ideally receive early and life-long Q10 therapy in order to prevent the disease from progressing and to avoid future organ damage.

Non-alcoholic fatty liver disease (NAFLD) is an insidious disease that is spreading like a bushfire, and it is typically seen in connection with overweight. Many people with the disease develop a type of liver inflammation and scarring that can be potentially life-threatening. According to a study that is published in Journal of Hepatology, supplementation with vitamin B12 and folic acid (vitamin B9) can counteract the development of inflammation and scarring by lowering levels of the amino acid homocysteine. The scientists behind the study looked closer at homocysteine’s role in the pathogenicity of the disease.

Cardiovascular disease is the leading cause of death worldwide but a new Dutch study has revealed that older patients who have suffered a previous heart attack can lower their risk of early death caused by cardiovascular disease and other causes by getting enough magnesium. Magnesium deficiencies are rather common because of unhealthy eating habits, and there are also certain types of medicine that impair the body’s ability to absorb and utilize magnesium.

Babies and small children are less likely to develop croup if their mothers have taken high-dosed vitamin D and fish oil during their pregnancy, according to a Danish study, where scientists have studied this relation for the very first time. Vitamin D and fish oil also benefit the child’s immune defense and counteract the inflammation in the respiratory system that triggers croup. The two supplements even have a positive impact on the child’s bone health and nervous system, and they also help prevent asthma.

Cystic fibrosis is a serious condition that affects the respiratory tract. It comes with chronic inflammation and sticky mucous and is known to cause early death. Patients who take high-dosed vitamin C supplements seem to make better use of vitamin E, which is also an antioxidant, and the result is less inflammation. This was seen in a study from Oregon State University. The scientists mention that taking extra vitamin C is also relevant for smokers and patients with metabolic disease.