Even short-term contact with cholesterol lowering drugs can cause potentially harmful side effects such as exercise intolerance and muscle pain, scientists report.

Statins, a widely used class of cholesterol-lowering drugs, are believed to cause exercise intolerance and damage muscle tissue. Now, a team of researchers from Columbia University – College of Physicians & Surgeons, have come one step closer to understanding why. Reporting in the June Archives of Neurology, the team of scientists describe how 34 patients on cholesterol-lowering medicine (atorvastatin) displayed significant reductions in their levels of coenzyme Q10, a vitamin-like substance which cells need in order to produce energy.

Cholesterol is a vital substance found in all cells and involved in many metabolic processes. Our bodies produce most of cholesterol according to its own needs, and the substance only becomes harmful if it oxidizes and gets embedded in the vessel walls. This has nothing to do with cholesterol levels being high or low. There is evidence that cholesterol-lowering statins inhibit the biosynthesis of Q10, vitamin D, vitamin K2, and several selenium-containing proteins. These compounds are important for energy production and serve as essential antioxidants that protect cholesterol from oxidative stress. Because of their reducing impact, statins often lead to fatigue, muscle weakness, oxidative stress, and other side effects that may eventually increase the risk of atherosclerosis, heart failure, and dementia. This is documented in numerous studies published over recent decades.

Surprisingly many people suffer from hypertension without knowing it. That is a concealed threat, as elevated blood pressure is a common cause of stroke and premature death. However, people with hypertension who take folic acid along with their blood pressure-lowering medicine have a substantially lower risk of stroke.

Medical science has claimed for decades that elevated cholesterol levels pose a health threat, especially if you have too much of the so-called “bad” cholesterol – or LDL (Low-Density Lipoprotein). However, a team of international experts is now arguing that this theory is exaggerated. In fact, the experts specifically advise against taking cholesterol-lowering statins. Meanwhile, science is focused on how to improve the safety of statins by combining them with supplements of coenzyme Q10.

There is absolutely no reason not to consume eggs, meat, butter and other cholesterol-filled foods with a good conscience. American dietary guidelines have finally exonerated cholesterol, which happens to be an essential compound. Many scientists actually claim that atherosclerosis and cardiovascular disease are both a result of inflammation and lack of specific micronutrients. It is important to pay attention to factors that are known to promote inflammation in the body and take the necessary steps by looking after your circulatory system, making healthy lifestyle choices, and possibly even using supplements.

Eat plenty of oily fish from clean oceans or take a fish oil supplement to make sure that you get enough of the essential omega-3 fatty acids. It lowers your risk of premature death by protecting you against atherosclerosis and a number of other diseases. In fact, blood levels of omega-3 tell a lot more than levels of cholesterol, according to a new study that is published in Journal of Clinical Lipidology.

The cellular energy turnover takes place inside some small powerhouses called mitochondria. The condition of these tiny structures is determining for our energy levels and health. That is why it is vital that the mitochondria are adequately supplied with all the necessary nutrients. Q10 and magnesium play a particularly important role.

Danish researchers have shed some light on the longstanding mystery: Why do we see so many people treated with cholesterol-lowering statins experiencing muscle pain and in some cases, also impaired glucose tolerance. The answer is a lack of Q10!

Cholesterol-lowering statins are associated with side effects such as aching muscles, fatigue, memory problems, diabetes, and poor sleep. At a molecular level, these drugs interfere with the body’s synthesis of Q10, which we need for cellular energy turnover. Moreover, Q10 is a powerful antioxidant that protects the cells against free radical damage. According to a review article published in the journal Cureus, Q10 supplements may lower side effects such as muscle pain.

Swedish scientists wrote medical history when they discovered that supplementation with Q10 and selenium could halve a person's risk of dying from cardiovascular disease. Now, a 10-year of the Swedish study shows that taking these two supplements even has a notable long-term effect on cardiac function and lifespan.

Cholesterol-lowering statins are among some of the most widely sold medical drugs. However, there is growing disagreement about their preventive effect on atherosclerosis and cardiovascular diseases, which are linked to many other factors than cholesterol levels alone. It turns out that statins also block the body’s production of vitamin K2, a nutrient that contributes to removing calcium from the bloodstream. A new study that is published in Medical Sciences concludes that atherosclerosis is more prevalent among statin users than among non-users, regardless of any cardiovascular diseases that have already been diagnosed. In other words, statins actually increase your risk of clogged-up arteries and that contradicts the traditional view. The new study supports earlier research, and it has been known for years that statins also block the endogenous synthesis of coenzyme Q10 and vitamin D, both of which are important for the heart and circulatory system.